Laura Denby

Affiliations

Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, EH16 4TJ, Edinburgh, EH16 4TJ, UK.

Publications (20)

Extracellular vesicle cross-talk between pulmonary artery smooth muscle cells and endothelium during excessive TGF-β signalling: implications for PAH vascular remodelling.

Cell communication and signaling : CCS

Avec: Fernando de la Cuesta , Ilaria Passalacqua , Julie Rodor , Raghu Bhushan , Laura Denby , Andrew H Baker

The function of miR-143, miR-145 and the MiR-143 host gene in cardiovascular development and disease.

Vascular pharmacology

Avec: Francesca Vacante , Laura Denby , Judith C Sluimer , Andrew H Baker

Sonoporation of Human Renal Proximal Tubular Epithelial Cells In Vitro to Enhance the Liberation of Intracellular miRNA Biomarkers.

Ultrasound in medicine & biology

Avec: Oliver Teenan , Vishal Sahni , Robert B Henderson , Bryan R Conway , Carmel M Moran , Jeremy Hughes , Laura Denby

MicroRNAs and their delivery in diabetic fibrosis.

Advanced drug delivery reviews

Avec: Alexa Wonnacott , Laura Denby , Richard J M Coward , Donald J Fraser , Timothy Bowen

Circulation research

Avec: Francesca Vacante , Julie Rodor , Mukesh K Lalwani , Amira D Mahmoud , Matthew Bennett , Azzurra L De Pace , Eileen Miller , Kim Van Kuijk , Jenny de Bruijn , Marion Gijbels , Thomas C Williams , Michael B Clark , Jessica P Scanlon , Amanda C Doran , Rusty Montgomery , David E Newby , Mauro Giacca , Dónal O'Carroll , Patrick W F Hadoke , Laura Denby , Judith C Sluimer , Andrew H Baker

Beta Blockade Prevents Cardiac Morphological and Molecular Remodelling in Experimental Uremia.

International journal of molecular sciences

Avec: Shanmugakumar Chinnappa , Azhar Maqbool , Hema Viswambharan , Andrew Mooney , Laura Denby , Mark Drinkhill

Stromal Cells Covering Omental Fat-Associated Lymphoid Clusters Trigger Formation of Neutrophil Aggregates to Capture Peritoneal Contaminants.

Immunity

Avec: Lucy Helen Jackson-Jones , Peter Smith , Jordan Raymond Portman , Marlène Sophie Magalhaes , Katie Jude Mylonas , Matthieu Marie Vermeren , Mark Nixon , Beth Emily Pollot Henderson , Ross Dobie , Sonja Vermeren , Laura Denby , Neil Cowan Henderson , Damian James Mole , Cécile Bénézech

T-Cell-Derived miRNA-214 Mediates Perivascular Fibrosis in Hypertension.

Circulation research

Avec: Ryszard Nosalski , Mateusz Siedlinski , Laura Denby , Eilidh McGinnigle , Michal Nowak , Aurelie Nguyen Dinh Cat , Laura Medina-Ruiz , Marco Cantini , Dominik Skiba , Grzegorz Wilk , Grzegorz Osmenda , Julie Rodor , Manuel Salmeron-Sanchez , Gerard Graham , Pasquale Maffia , Delyth Graham , Andrew H Baker , Tomasz J Guzik

Identifying cell-enriched miRNAs in kidney injury and repair.

JCI insight

Avec: Katie L Connor , Oliver Teenan , Carolynn Cairns , Victoria Banwell , Rachel Ab Thomas , Julie Rodor , Sarah Finnie , Riinu Pius , Gillian M Tannahill , Vishal Sahni , Caroline Os Savage , Jeremy Hughes , Ewen M Harrison , Robert B Henderson , Lorna P Marson , Bryan R Conway , Stephen J Wigmore , Laura Denby

Myeloid Heterogeneity in Kidney Disease as Revealed through Single-Cell RNA Sequencing.

Kidney360

Avec: Rachel M B Bell , Laura Denby

Refining the Mouse Subtotal Nephrectomy in Male 129S2/SV Mice for Consistent Modeling of Progressive Kidney Disease With Renal Inflammation and Cardiac Dysfunction.

Frontiers in physiology

Avec: James O'Sullivan , Sarah Louise Finnie , Oliver Teenan , Carolynn Cairns , Andrew Boyd , Matthew A Bailey , Adrian Thomson , Jeremy Hughes , Cécile Bénézech , Bryan Ronald Conway , Laura Denby

MIR503HG Loss Promotes Endothelial-to-Mesenchymal Transition in Vascular Disease.

Circulation research

Avec: João P Monteiro , Julie Rodor , Axelle Caudrillier , Jessica P Scanlon , Ana-Mishel Spiroski , Tatiana Dudnakova , Beatrice Pflüger-Müller , Alena Shmakova , Alex von Kriegsheim , Lin Deng , Richard S Taylor , John R Wilson-Kanamori , Shiau-Haln Chen , Kevin Stewart , Adrian Thomson , Tijana Mitić , John D McClure , Jean Iynikkel , Patrick W F Hadoke , Laura Denby , Angela C Bradshaw , Paola Caruso , Nicholas W Morrell , Jason C Kovacic , Igor Ulitsky , Neil C Henderson , Andrea Caporali , Matthias S Leisegang , Ralf P Brandes , Andrew H Baker

Transfer of hepatocellular microRNA regulates cytochrome P450 2E1 in renal tubular cells.

EBioMedicine

Avec: Olivia Matthews , Emma E Morrison , John D Tranter , Philip Starkey Lewis , Iqbal S Toor , Abhishek Srivastava , Rebecca Sargeant , Helen Rollison , Kylie P Matchett , Timothy J Kendall , Gillian A Gray , Chris Goldring , Kevin Park , Laura Denby , Neeraj Dhaun , Matthew A Bailey , Neil C Henderson , Dominic Williams , James W Dear

Kidney Single-Cell Atlas Reveals Myeloid Heterogeneity in Progression and Regression of Kidney Disease.

Journal of the American Society of Nephrology : JASN

Avec: Bryan R Conway , Eoin D O'Sullivan , Carolynn Cairns , James O'Sullivan , Daniel J Simpson , Angela Salzano , Katie Connor , Peng Ding , Duncan Humphries , Kevin Stewart , Oliver Teenan , Riinu Pius , Neil C Henderson , Cécile Bénézech , Prakash Ramachandran , David Ferenbach , Jeremy Hughes , Tamir Chandra , Laura Denby

Role of Tim4 in the regulation of ABCA1

Nature communications

Avec: M S Magalhaes , P Smith , J R Portman , L H Jackson-Jones , C C Bain , P Ramachandran , Z Michailidou , R H Stimson , M R Dweck , L Denby , N C Henderson , S J Jenkins , C Bénézech

Endothelin-1 Mediates the Systemic and Renal Hemodynamic Effects of GPR81 Activation.

Hypertension (Dallas, Tex. : 1979)

Avec: Natalie K Jones , Kevin Stewart , Alicja Czopek , Robert I Menzies , Adrian Thomson , Carmel M Moran , Carolynn Cairns , Bryan R Conway , Laura Denby , Dawn E W Livingstone , John Wiseman , Patrick W Hadoke , David J Webb , Neeraj Dhaun , James W Dear , John J Mullins , Matthew A Bailey

P2X7 receptor knockout does not alter renal function or prevent angiotensin II-induced kidney injury in F344 rats.

Scientific reports

Avec: Josselin Nespoux , Marie-Louise T Monaghan , Natalie K Jones , Kevin Stewart , Laura Denby , Alicja Czopek , John J Mullins , Robert I Menzies , Andrew H Baker , Matthew A Bailey

Single-cell analysis of senescent epithelia reveals targetable mechanisms promoting fibrosis.

JCI insight

Avec: Eoin D O'Sullivan , Katie J Mylonas , Rachel Bell , Cyril Carvalho , David P Baird , Carolynn Cairns , Kevin M Gallagher , Ross Campbell , Marie Docherty , Alexander Laird , Neil C Henderson , Tamir Chandra , Kristina Kirschner , Bryan Conway , Gry H Dihazi , Michael Zeisberg , Jeremy Hughes , Laura Denby , Hassan Dihazi , David A Ferenbach

Indian Hedgehog release from TNF-activated renal epithelia drives local and remote organ fibrosis.

Science translational medicine

Avec: Eoin D O'Sullivan , Katie J Mylonas , Cuiyan Xin , David P Baird , Cyril Carvalho , Marie-Helena Docherty , Ross Campbell , Kylie P Matchett , Scott H Waddell , Alexander D Walker , Kevin M Gallagher , Siyang Jia , Steve Leung , Alexander Laird , Julia Wilflingseder , Michaela Willi , Maximilian Reck , Sarah Finnie , Angela Pisco , Sabrina Gordon-Keylock , Alexander Medvinsky , Luke Boulter , Neil C Henderson , Kristina Kirschner , Tamir Chandra , Bryan R Conway , Jeremy Hughes , Laura Denby , Joseph V Bonventre , David A Ferenbach

Mapping cardiac remodeling in chronic kidney disease.

Science advances

Avec: Nadine Kaesler , Mingbo Cheng , James Nagai , James O'Sullivan , Fabian Peisker , Eric M J Bindels , Anne Babler , Julia Moellmann , Patrick Droste , Giulia Franciosa , Aurelien Dugourd , Julio Saez-Rodriguez , Sabine Neuss , Michael Lehrke , Peter Boor , Claudia Goettsch , Jesper V Olsen , Thimoteus Speer , Tzong-Shi Lu , Kenneth Lim , Jürgen Floege , Laura Denby , Ivan Costa , Rafael Kramann

Réseau de co-auteurs

Andrew H Baker 6 collaborations

Jeremy Hughes 6 collaborations

Julie Rodor 5 collaborations

Bryan R Conway 5 collaborations

Carolynn Cairns 5 collaborations

Neil C Henderson 5 collaborations

Oliver Teenan 4 collaborations

Matthew A Bailey 4 collaborations

Kevin Stewart 4 collaborations

Cécile Bénézech 3 collaborations

James O'Sullivan 3 collaborations

Adrian Thomson 3 collaborations

Eoin D O'Sullivan 3 collaborations

Tamir Chandra 3 collaborations

Francesca Vacante 2 collaborations

Judith C Sluimer 2 collaborations

Vishal Sahni 2 collaborations

Robert B Henderson 2 collaborations

Carmel M Moran 2 collaborations

Jessica P Scanlon 2 collaborations

Patrick W F Hadoke 2 collaborations

Sarah Finnie 2 collaborations

Riinu Pius 2 collaborations

Kylie P Matchett 2 collaborations

Neeraj Dhaun 2 collaborations

James W Dear 2 collaborations

Natalie K Jones 2 collaborations

Alicja Czopek 2 collaborations

Robert I Menzies 2 collaborations

John J Mullins 2 collaborations

Katie J Mylonas 2 collaborations

Cyril Carvalho 2 collaborations

David P Baird 2 collaborations

Kevin M Gallagher 2 collaborations

Ross Campbell 2 collaborations

Alexander Laird 2 collaborations

Kristina Kirschner 2 collaborations

David A Ferenbach 2 collaborations

Fernando de la Cuesta 1 collaboration

Ilaria Passalacqua 1 collaboration

Raghu Bhushan 1 collaboration

Alexa Wonnacott 1 collaboration

Richard J M Coward 1 collaboration

Donald J Fraser 1 collaboration

Timothy Bowen 1 collaboration

Mukesh K Lalwani 1 collaboration

Amira D Mahmoud 1 collaboration

Matthew Bennett 1 collaboration

Azzurra L De Pace 1 collaboration

Eileen Miller 1 collaboration

Kim Van Kuijk 1 collaboration

Jenny de Bruijn 1 collaboration

Marion Gijbels 1 collaboration

Thomas C Williams 1 collaboration

Michael B Clark 1 collaboration

Amanda C Doran 1 collaboration

Rusty Montgomery 1 collaboration

David E Newby 1 collaboration

Mauro Giacca 1 collaboration

Dónal O'Carroll 1 collaboration

Shanmugakumar Chinnappa 1 collaboration

Azhar Maqbool 1 collaboration

Hema Viswambharan 1 collaboration

Andrew Mooney 1 collaboration

Mark Drinkhill 1 collaboration

Lucy Helen Jackson-Jones 1 collaboration

Peter Smith 1 collaboration

Jordan Raymond Portman 1 collaboration

Marlène Sophie Magalhaes 1 collaboration

Katie Jude Mylonas 1 collaboration

Matthieu Marie Vermeren 1 collaboration

Mark Nixon 1 collaboration

Beth Emily Pollot Henderson 1 collaboration

Ross Dobie 1 collaboration

Sonja Vermeren 1 collaboration

Neil Cowan Henderson 1 collaboration

Damian James Mole 1 collaboration

Ryszard Nosalski 1 collaboration

Mateusz Siedlinski 1 collaboration

Eilidh McGinnigle 1 collaboration

Michal Nowak 1 collaboration

Aurelie Nguyen Dinh Cat 1 collaboration

Laura Medina-Ruiz 1 collaboration

Marco Cantini 1 collaboration

Dominik Skiba 1 collaboration

Grzegorz Wilk 1 collaboration

Grzegorz Osmenda 1 collaboration

Manuel Salmeron-Sanchez 1 collaboration

Gerard Graham 1 collaboration

Pasquale Maffia 1 collaboration

Delyth Graham 1 collaboration

Tomasz J Guzik 1 collaboration

Katie L Connor 1 collaboration

Victoria Banwell 1 collaboration

Rachel Ab Thomas 1 collaboration

Gillian M Tannahill 1 collaboration

Caroline Os Savage 1 collaboration

Ewen M Harrison 1 collaboration

Lorna P Marson 1 collaboration

Stephen J Wigmore 1 collaboration

Rachel M B Bell 1 collaboration

Sarah Louise Finnie 1 collaboration

Andrew Boyd 1 collaboration

Bryan Ronald Conway 1 collaboration

João P Monteiro 1 collaboration

Axelle Caudrillier 1 collaboration

Ana-Mishel Spiroski 1 collaboration

Tatiana Dudnakova 1 collaboration

Beatrice Pflüger-Müller 1 collaboration

Alena Shmakova 1 collaboration

Alex von Kriegsheim 1 collaboration

Lin Deng 1 collaboration

Richard S Taylor 1 collaboration

John R Wilson-Kanamori 1 collaboration

Shiau-Haln Chen 1 collaboration

Tijana Mitić 1 collaboration

John D McClure 1 collaboration

Jean Iynikkel 1 collaboration

Angela C Bradshaw 1 collaboration

Paola Caruso 1 collaboration

Nicholas W Morrell 1 collaboration

Jason C Kovacic 1 collaboration

Igor Ulitsky 1 collaboration

Andrea Caporali 1 collaboration

Matthias S Leisegang 1 collaboration

Ralf P Brandes 1 collaboration

Olivia Matthews 1 collaboration

Emma E Morrison 1 collaboration

John D Tranter 1 collaboration

Philip Starkey Lewis 1 collaboration

Iqbal S Toor 1 collaboration

Abhishek Srivastava 1 collaboration

Rebecca Sargeant 1 collaboration

Helen Rollison 1 collaboration

Timothy J Kendall 1 collaboration

Gillian A Gray 1 collaboration

Chris Goldring 1 collaboration

Kevin Park 1 collaboration

Dominic Williams 1 collaboration

Daniel J Simpson 1 collaboration

Angela Salzano 1 collaboration

Katie Connor 1 collaboration

Peng Ding 1 collaboration

Duncan Humphries 1 collaboration

Prakash Ramachandran 1 collaboration

David Ferenbach 1 collaboration

M S Magalhaes 1 collaboration

P Smith 1 collaboration

J R Portman 1 collaboration

L H Jackson-Jones 1 collaboration

C C Bain 1 collaboration

P Ramachandran 1 collaboration

Z Michailidou 1 collaboration

R H Stimson 1 collaboration

M R Dweck 1 collaboration

L Denby 1 collaboration

N C Henderson 1 collaboration

S J Jenkins 1 collaboration

C Bénézech 1 collaboration

Dawn E W Livingstone 1 collaboration

John Wiseman 1 collaboration

Patrick W Hadoke 1 collaboration

David J Webb 1 collaboration

Josselin Nespoux 1 collaboration

Marie-Louise T Monaghan 1 collaboration

Rachel Bell 1 collaboration

Marie Docherty 1 collaboration

Bryan Conway 1 collaboration

Gry H Dihazi 1 collaboration

Michael Zeisberg 1 collaboration

Hassan Dihazi 1 collaboration

Cuiyan Xin 1 collaboration

Marie-Helena Docherty 1 collaboration

Scott H Waddell 1 collaboration

Alexander D Walker 1 collaboration

Siyang Jia 1 collaboration

Steve Leung 1 collaboration

Julia Wilflingseder 1 collaboration

Michaela Willi 1 collaboration

Maximilian Reck 1 collaboration

Angela Pisco 1 collaboration

Sabrina Gordon-Keylock 1 collaboration

Alexander Medvinsky 1 collaboration

Luke Boulter 1 collaboration

Joseph V Bonventre 1 collaboration

Nadine Kaesler 1 collaboration

Mingbo Cheng 1 collaboration

James Nagai 1 collaboration

Fabian Peisker 1 collaboration

Eric M J Bindels 1 collaboration

Anne Babler 1 collaboration

Julia Moellmann 1 collaboration

Patrick Droste 1 collaboration

Giulia Franciosa 1 collaboration

Aurelien Dugourd 1 collaboration

Julio Saez-Rodriguez 1 collaboration

Sabine Neuss 1 collaboration

Michael Lehrke 1 collaboration

Peter Boor 1 collaboration

Claudia Goettsch 1 collaboration

Jesper V Olsen 1 collaboration

Thimoteus Speer 1 collaboration

Tzong-Shi Lu 1 collaboration

Kenneth Lim 1 collaboration

Jürgen Floege 1 collaboration

Ivan Costa 1 collaboration

Rafael Kramann 1 collaboration